Our Medical Specialties Doctors
Hemen Arayın

Expertise & Areas of interest

  • Reproductive Endocrinology and Infertility Assisted Reproduction Treatments: IVF Endoscopic Surgery: Laparoscopy – Hysteroscopy

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Assoc. Prof. Dr. Tayfun Kutlu graduated from Istanbul University Istanbul Medical Faculty in 1991. He completed his residency training on Obstetrics and Gynecology in Istanbul Zeynep Kamil Obstetrics and Pediatrics Training and Research Hospital between 1992-1996. He undertook the position of IVF Center Unit Supervisor as of 2014 in IVF Center of Zeynep Kamil Obstetrics and Pediatrics Training and Research Hospital, where he served between 2000-2019. In 2017, he was granted the title of Associate Professor and Training Officer. He continues to work as the Director of IVF Center of Anadolu Medical Center Hospital, where he's taken office in early 2020.


Istanbul University, Istanbul Faculty of Medicine 1985-1991
Istanbul Zeynep Kamil Obstetrics and Pediatrics Training and Research Hospital 1992-1996



1. Kutlu T, Özkaya E, Şanverdi I, Çakar E, Ayvacı H, Devranoğlu B, Karateke A. Acute fetal heart rate tracing changes secondary to cigarette smoking in third trimester pregnancies. The Journal of Maternal Fetal Neonatal Medicine, 2017 30(12),1407-1409.

2. Kutlu T, Özkaya E, Ayvacı H, Devranoğlu B, Şanverdi İ, Şahin Y, Şenol T, Karateke A. Area under curve of temporal estradiol measurements for prediction of the detrimental effect of estrogen exposure on implantation. International Journal of Gynecology and Obstetrics, 2016, 135(2),168-171.

3. Kutlu T, TuğrulS, Aydın A, Oral Ö. Tuberculous meningitis in pregnancy presenting as hyperemesis gravidarum. J Matern Fetal Neonatal Med. 2007 Apr;20(4):357-9.

4. Kutlu T, Tuğrul S, Aran T, Uslu H, Eren S, Oral Ö. Combined administration of misoprostol in the first and second trimester missed abortion cases. Clin Exp Obstet Gynecol. 2006;33(4):226-8.

5. Kutlu T, Ficicoglu C, Başaran T, Başaran E, Topaloğlu T. Mammographic breast density changes after 1 year of tibolone use. Maturitas. 2004 Jun 15;48(2):133-6.

6. Ozkaya E, Kutlu T, Abide Yayla C, Kayatas Eser S, Sanverdi I, Devranoglu B. Area under the curve of temporal estrogen and progesterone measurements during assisted reproductive technology: Which hormone is the main determinant of cycle outcome? J Obstet Gynaecol Res. 2018; 44(2):263-269.

7. Sanverdi I, Kutlu T, Bilgic BE, Incebiyik A. A comparison of treatment results of the different treatment protocols in patients with poor ovarian response. Gynecol Endocrinol. 2018; 34(6):524-527.

8. Kara M, Kutlu T, Sofuoglu K, Devranoglu B, Cetinkaya T. Association between serum estradiol level on the hCG administration day and IVF-ICSI outcome. Iran J Reprod Med. 2012, 10(1),53-58.

9. Tuğrul S, Kutlu T, Pekin O, Bağlam E, Kıyak H, Oral Ö. Clinical, endocrine and metabolic effects of acarbose, alpha glucosidase inhibitor, in overweight and non-overweight PCOS patients. Fertil Steril. 2008 Oct;90(4):1144-8

10. Ficicioglu C, Kutlu T, Baglam E, Bakacak Z. Early follicular antimullerian hormone as an indicator of ovarian reserve. Fertil Steril. 2006 Mar;85(3):592-6.

11. Oral O, Kutlu T, Aksoy E, Ficicioglu C, Uslu H, Tugrul S. The effects of oxidative stress on outcomes of assisted reproductive techniques. J Assist Reprod Genet. 2006 Feb;23(2):81-5.

12. Ficicioglu C, Kutlu T, Taşdemir S, Altuntaş L. The effects of different gonadotropin releasing hormone analogues in IVF cycles. MEFSJ. 2005; 10(3): 212-8.

13. Ficicioglu C, Kutlu T, Demirbasoglu S, Mulayim B. The role of inhibin B as a basal determinant of ovarian reserve. Gynecol Endocrinol. 2003 Aug;17(4):287-93.

14. Ficicioglu C, Kutlu T. The role of androgens in the aetiology and pathology of pre-eclampsia. J Obstet Gynaecol. 2003 Mar;23(2):134-7.

15. Çakar E, Yavuz MM, Kutlu T, Ayvacı Taşan H, Cogendez E, Beydilli Nacak G, Özkaya E, Kayataş Eser S. Ivf versus spontan singleton pregnancies fetal and maternal outcomes in a tertiary care hospital. International Journal of Medical Science and Clinical Invention 2018, 5(03): 3583-3587. 

16. Kara M, Sofuoglu K, Kutlu T, Devranoglu B, Çetinkaya T.Comparison of the efficacy and cost-effectiveness of highly purified urinary follicle stimulating hormone (HP-uFSH) and recombinant follicle stimulating hormone (r FSH) in poor responders.  Journal of the Dow University of Health Sciences Karachi 2011, Vol. 5 (2): 43-46

17. Yiginer O, Dogan M, Gun I, Kutlu T, Degirmencioglu G, Guliyev İ, Tokatli A, Kilicaslan F. The effects of supraphysiological estrogen levels on ventricular repolarization parameters. Kardiol Pol. 2018 Feb 5. doi: 10.5603/KP.a2018.0037.

18. Şahin Y, Özkaya E, Kayataş Eser S, Kutlu T, Şanverdi İ, Tunalı G, Karateke A. Serum substance P concentrations to predict oocyte maturation index and clinical pregnancy. Gynecological Endocrinology, 2017, 33(3), 203-207.

19. Aydın GA, Yavuz A, Terzi H, Kutlu T. Assessment of the relationship of basal serum anti-mullerian hormone levels with oocyte quality and pregnancy outcomes in patients undergoing ICSI. Iran J Reprod Med 2015, 13(4), 231-236.

20. Tugrul S, Oral O, Guclu M, Kutlu T, Uslu H, Pekin O. Significance of Doppler ultrasonography in the diagnosis of polycystic ovary syndrome. Clin Exp Obstet Gynecol. 2006;33(3):154-8.

21. Tugrul S, Yildirim G, Pekin O, Uslu H, Kutlu T, Eren S. Comparison of two forms of continuous combined hormone replacement therapy with respect to metabolic effects. Arch Gynecol Obstet. 2007 May;275(5):335-9.

22. Çakar E, Ayvaci Tasan H, Kumru P, Cogendez E, Tarhan N, Kutlu T, Özkaya E, Kayatas Eser S. Combined use of oestradiol and progesterone to support luteal phase in antagonist intracytoplasmic sperm injection cycles of normoresponder women: a case-control study. Journal of Obstetrics and Gynaecology. 2019, 1-6.

23. Kurek Eken M, Sahin Ersoy G, Yayla Abide Ç, Sanverdi İ, Devranoglu B, Kutlu T, Çevik Ö. Association between circulating neuregulin 4 levels and metabolic, aterogenic, and AMH profile of polycystic ovary syndrome. Journal of Obstetrics and Gynaecology. 2019,1-6. 

24. Abide Yayla C, Ozkaya E, Beydilli Nacak G, Sanverdi I, Devranoglu B, Bostanci Ergen E, Kilicci C, Kutlu T. High estrogen exposure may not be detrimental on endometrial receptivity in women with PCOS. Gynecol Endocrinol. 2018; 34(9), 798-803.

25. Abide Yayla Ç, Özkaya E, Kayataş Eser S, Şanverdi İ, Devranoğlu B, Kutlu T. Association of basal serum androgen levels with ovarian response and ICSI cycle outcome. Ir J Med Sci. 2018; 187(2):409-415.

26. Ovayolu A, Özdamar Ö, Gün İ, Arslanbuğa CY, Kutlu T, Tunalı G,Uluhan R.The assesment of follicular fluid presepsin levels in poor ovarian responder women and its relationship with the reproductive outcomes. Int J Clin Exp Med 2015;8(6):9961-9966.

27. Bilgic BE. Yayla Abide C. Ozkaya E. Kutlu T. Ayla Ş.Şanverdi İ. Tunalı G. Yucel E. Kanbur S. Role of Oocyte Morphological Abnormality Rates on the Embryo Development and Implantation. Gynecol Obstet Reprod Med 2018; DOI:10.21613/GORM.2018.755

28. Bozdağ H, Akdeniz E, Devranoğlu B, Haksever M, Bilgiç BE, Kutlu T. Cytoplasmic abnormalities of mature oocytes have a significant effect on fertilization in Bologna poor responders. Turkish journal of medical sciences. 2018; 48(4), 750-758.

29. Yayla Abide Ç. Özkaya E. Kayataş Eser S. Devranoğlu B. Bilgiç BE. Kutlu T. Serum Albumin Level Adjusted Progesterone Level on the Trigger Day is Not a Significant Predictor of Clinical Pregnancy. Gynecol Obstet Reprod Med 2018; DOI:10.21613/GORM.2017.771

30. Devranoglu B. Yayla Abide Ç, Özkaya E. Şenol T. Kutlu T. Kayatas Eser S. Coagulation Tests at Trigger Day in Patients with Factor V Leiden Mutation to Predict Implantation Failure.Gynecol Obstet Reprod Med 2018; DOI:10.21613/GORM.2017.754

31. E Özkaya, ÇA Yayla, SK Eser, B Devranoğlu, I Şanverdi, T Kutlu (2018). Short Term Alterations of Hormone Profile Following Oocyte Pick-Up in Women with Polycystic Ovarian Syndrome to Assess the Effect of Multiple Needle Entries Into The Ovarian Cortex and Stroma. Gynecology Obstetrics & Reproductive Medicine 24 (1), 17-21

32. Çakar E, Yavuz MM, Kutlu T, Ayvacı Taşan H, Cogendez E,  Beydilli Nacak G, Özkaya E, Eser SK (2018). Ivf versus spontan singleton pregnancies fetal and maternal outcomes in a tertiary care hospital. International Journal of Medical Science and Clinical invention; 5(3), 3583-3587.

33. BE Bilgiç, E Özkaya, T Kutlu, SK Eser, İ Sanverdi, SB Türkmen (2017). Transvajinal Folikül Aspirasyonunu Takiben Oosit Toplanabilen ve Toplanamayan Kötü Yanıtlı Hastaların Siklus Karakteristiklerinin Karşılaştırılması. Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi 14 (4)

34. Kutlu T, Özkaya E, Kumru P, Ayvacı H, Devranoğlu B, Şanverdi İ, Şahin Y, Sağlam B, Karateke A (2017). Clinical analyses of successful and previously failed intracytoplasmic sperm injection cycle parameters in patients with poor ovarian reserve. Turkish Journal of Obstetrics and Gynecology, 2017 Mar;14(1):58-63.

35. Özkaya E. Şahin Y. Kayataş Eser S. Albayrak B. Bulduk O. Sanverdi İ. Kutlu T (2017). Does the Modification of Starting Gonadotropin Dose During ICSI Cycle Have Any Significant Impact on Cycle Outcome? Gynecol Obstet Reprod Med; 23(3):138-142

36. Kutlu H T, Özkaya E, Sanverdi I, Devranoğlu B, Ipekçi C, Konukçu B, Yavuz S, Karateke A (2016). Relationship Between The Estradiol- Progesterone Alterations After Ovulation Trigger And Treatment Success In IUI Cycles. Turk J Obstet Gynecol;13:56-61

37. Şanverdi İ, Özkaya E, Kutlu T, Şenol T, Akalın M, Akalın E S, Şahin Y, Karateke A (2016). Non-invasive prediction of implantation window in controlled hyperstimulation cycles: Can the time from the menstrual day at embryo transfer to expected menstrual cycle give a clue? Turkish Journal of Obstetrics and Gynecology, 13, 116-22.

38. Özüm G, Özdamar Ö, Gün I, Sofuoğlu K, Kutlu H T, Tunalı G (2016). Histeroskopi yapılan primer ve sekonder infertil hastalarda histerosalpingografi ve transvaginal ultrasonografinin tanısal degerinin incelenmesi. Zeynep Kamil Tıp Bülteni, 47(1), 1-5. Doi: 10.16948/zktb.08928

39. Selçuk S, Küçükbaş M, Yenidede I, Kayataş Eser S, Eser A, Çam Ç, Kutlu H T (2016). The outcomes of controlled ovarian hyperstimulation/intrauterine insemination in patients with unilateral tubal occlusion on hysterosalpingograph. Turkish Journal of Obstetrics and Gynecology, 13(1), 7-10

40. Selçuk S, Özkaya E, Eser A, Kuyucu M, Kutlu H T, Devranoğlu B, Sofuoğlu K, Dayıcıoğlu V E (2016). Characteristics and outcomes of in vitro fertilization in different phenotypes of polycystic ovary syndrome. Turkish Journal of Obstetrics and Gynecology, 13(1), 1-6.

41. Temizkan O, Çöğendez E, Sanverdi I, Temizkan S, Kutlu H T, Ayhan I, Arıcı B, Aşıcıoğlu O (2015). GnRH agonist veya antagonist ile down regülasyon yapılan ICSI/ET sikluslarında insan koryonik gonadotropin günü bakılan estradiol, prolaktin düzeylerinin embriyo kalitesi ve gebelik sonuçlarına etkisi. Sişli Etfal Hastanesi Tip Bulteni / The Medical Bulletin of Sisli Hospital, 49(3), 174-180., Doi: 10.5350/SEMB. 20150302090129

42. Ayla Ş, Tunalı G, Körkoca N, Beyhan Sağlam, Ural M, Sofuoğlu K, Uslu B, Kutlu T, Devranoğlu B, Büyükbayrak EE, Şahin S. Tek ve Şartlı İki Embryo Transfer (Yönetmeliği) Sonrası Gebelik Oranları. Zeynep Kamil Tıp Bülteni,45 (4), 156-159, 2014

43. Baykal B, Çelik C, Bastu E, Kutlu T, Batu P, Abalı R, Eren S. Effect of Antral Follicle Count on in Vitro Fertilization Outcome. Antral Folikül Sayısının in Vitro Fertilizasyon Sonuçlari Üzerine Etkisi. J Clin Anal Med,, 5(4): 324-7, 2014 
44. Şahin S, Selçuk S, Devranoğlu B, Kutlu T, Kuyucu M, Eroğlu M. Comparison of long GnRH agonist versus GnRH antagonist protocol in poor responders. J Turk Soc Obstet Gynecol,11, 203-206,2014.

45. Kara M, Kutlu T, Sofuoğlu K. Comparison of the Recombinant Versus Highly-Purified, Urinary Follicle-Stimulating Hormone (r-FSH vs. HP-uFSH) in the Polycystic Ovary Syndrom Patients who had Antagonist Cycle with In Vitro Fertilization-Embryo Transfer. Turkiye Klinikleri J Med Sci, 31(4):775-9, 2011.

46. Gürleyiğ E, Sanverdi I, Kutlu H T, Muyır R, Eren S (2007). Benign Adneksial Kitlelerin Laparoskopik Yönetimi. Haydarpasa Numune Egitim ve Arastırma Hastanesi Tıp Dergisi, 47(4), 469-473.

47. Kutlu H T, Aran T, Oral Ö, Gürleyiğ E, Altınkaş K, Önal G (2007). Perimenopozal Dönemde Molar Gebelik. Haydarpasa Numune Egitim ve Arastırma Hastanesi Tıp Dergisi, 47(1).

48. Aköz I, Ayas S, Kutlu H T, Pekin O, Eren S (2006). Tuba Uterina Leiomyomu. Zeynep Kamil Tıp Bülteni, 37(4), 95-96

49. Kutlu H T, Tuğrul A S, Çeçen F, Eren S (2006). Endometrial Örnekleme Öncesi Misoprostol Kullanımı. Kadın Dogum Dergisi, 4(4), 909-913

50. Gürleyiğ E, Kutlu H T, Altınkaş K, Önal G, Oral Ö (2006). Ektopik Gebeligin Yönetiminde Genel Hastane Deneyimimiz: Tedavi Seçiminde Cerrahı Etkileyen Faktörler. Kadın Dogum Dergisi, 5(1), 1006-1009

51. Kutlu T, Bağlam E, Genç Z, Eren S. Erken Doğum Tehditini Önceden Belirlemede Risk Puanı, Servikal Uzunluk ve Maternal Tükrük Östriol Seviyesinin Rolü. Zeynep Kamil Tıp Bülteni Jinekoloji-Obstetrik-Pediatri Klinikleri, 36 ( 2 ), 51 – 55, 2005.

52. Kutlu T, Bağlam E, Eren S. Twın Pregnancy Complıcated By Interlocking:A Case Report. Gynecology, Obstetrics & Reproductive Medicine,  GORM,12 (1),47-49, 2006

53. Usta SS, Kutlu T, Eren S. Do Tibolone and Combined Hormone Replacement Therapy Have a Beneficial Effect on Plasma Lipid Levels in Hyper and Normocholesterolemic Postmenopausal Women? Gynecology, Obstetrics & Reproductive Medicine ( GORM ), 10 ( 3 ), 186 – 190, 2004.

54. Fıçıcıoğlu C, Kutlu T, Başaran T, Yaltı S, Gürbüz B, Taşdemir S. Yardımcı Üreme Tekniklerinde Kontrollü Over Hiperstimülasyon İçin Rekombinant FSH  ve  ile Saf Üriner FSH Kullanımının Karşılaştırılması. Klinik Bilimler & Doktor Dergisi, 10 ( 5 ), 579 – 584,  2004.

55. Aköz İ, Kılıçcı Ç, Kutlu T, Pekin O, Eren S. Sezaryen Sırasında Tesadüfen Saptanmış Adneksiyal Kitleler. Zeynep Kamil Tıp Bülteni Jinekoloji-Obstetrik-Pediatri Klinikleri, 35 ( 2 ), 61 – 65, 2004.

56. Kutlu T, Bozdağ H, Aköz İ, Pekin O, Usta S, Eren S. Sezaryen Sonrası Opioid Gereksinimini Azaltmada Tek Doz İndometasin Supozituar Kullanımının Yeri. Zeynep Kamil Tıp Bülteni Jinekoloji-Obstetrik-Pediatri Klinikleri, 34 ( 3 ), 1 – 4, 2003.

57. Bozdağ H, Ertekin K, Kutlu T, Öztürk G, Eren S. Akut Faz Reaktanı Olarak Ferritin ve Erken Doğum Tehdidinde Kullanımı. Zeynep Kamil Tıp Bülteni Jinekoloji-Obstetrik-Pediatri Klinikleri, 34 ( 1 ), 13-18, 2003.

58. Kutlu T, Başaran T, Fıçıcıoğlu C. Yardımcı Üreme Tekniklerinde Eksojen HCG Uygulama Günü E2 Düzeyinin Prognostik Değeri. Zeynep Kamil Tıp Bülteni Jinekoloji-Obstetrik-Pediatri Klinikleri, 33 ( 2 ), 1-4, 2002.

59. Tuğrul S, Köse G, Kutlu T, Demirören T. İntrauterin Gelişme Geriliğinde Maternal Serum Albümin ve Prealbümin Düzeyleri. Jinekoloji ve Obstetrik Dergisi, 13(2): 107-111, 1999.

60. Kara M, Tuğrul S, Kekovalı M, Özden S, Kutlu T, Eroğlu M. Kistik Ovarian Tümörlerde Video Laparoskopik Yaklaşım. Endoskopik Laparoskopik Minimal İnvaziv Cerrahi, 3 (3): 162-167, 1996.

61. Çetin A, Kara M, Kutlu T, Cantekin D. Gebelikte Asemptomatik Bakteriüri ve Maternal Anemi İle İlişkisi. Zeynep Kamil Tıp Bülteni Jinekoloji-Obstetrik-Pediatri Klinikleri, 28 ( 4 ): 260-263, 1996.

62. Fıçıcıoğlu C, Kalay B, Cantekin D, Ünlü R, Solmaz E,  Kutlu T. Prematür Membran Rüptürü Olgularında Muhtemel Risk Faktörlerinin İrdelenmesi. PTT Hastanesi Tıp Dergisi, 17 ( 3 ): 289-298, 1995.

63. Çetin A, Kara M, Kutlu T, Cantekin D. İntraservikal Prostoglandin E2 Jel Aplikasyonu İle Doğum İndüksiyonu. PTT Hastanesi Tıp Dergisi, 16 ( 3 ): 289-294, 1994.

64. Kalay B, Fıçıcıoğlu C, Gürbüz A, Kumru A, Kutlu T. Fetal Solunum Hareketi ve NST: Preterm Prematür Membran Rüptüründe Koryoamnionit ve Perinatal Enfeksiyon Riskini Saptamada Zayıf Belirtiler. PTT Hastanesi Tıp Dergisi, 16 ( 2 ): 141-148, 1994.

65. Gürbüz A, Fıçıcıoğlu C, Kutlu T, Kalay B. Serviksin Premalign Lezyonlarına Güncel Yaklaşım. PTT Hastanesi Tıp Dergisi, 16 ( 2 ): 121-127, 1994.

66. Gürbüz A, Fıçıcıoğlu C, Kalay B, Kutlu T. Tekrarlayan Gebelik Kayıplarının Otoimmün Boyutu. PTT Hastanesi Tıp Dergisi, 16 ( 3 ): 279-287, 1994.

67. Fıçıcıoğlu C, Yıldırım A, Ünlü R, Cantekin D, Kutlu T. Erken Gebelik Bulantı ve Kusmalarında HCG’in Rolü. PTT Hastanesi Tıp Dergisi, 15 (3): 343-357, 1993.

68. Akın S,  Fıçıcıoğlu C, Ünlü R, Cantekin D, Kutlu T. Perimenopozal Anormal Uterin Kanamalı Hastaların Endovajinosonografik Endometrial Kalınlık Değerlendirilmeleri. PTT Hastanesi Tıp Dergisi, 15 ( 3 ): 331-338, 1993.

69. Fıçıcıoğlu C, Ertekin K, Ünlü R, Kutlu T. HAIR-AN Sendromu. PTT Hastanesi Tıp Dergisi, 15 ( 1 ): 101-109, 1993.

Course Participation

1.     Recent Advances in ART, 6th MSRM Congress, Antalya, 19.04.2007
2. Practical Course for Diagnostic and Therapeutic Hysteroscopy, Hysteroscopy practices training, Zeynep Kamil Obstetrics and Pediatrics Training and Research Hospital, 14.06.2005
3. Advanced Course On Perinatal Ultrasound, First-Second Trimester Scanning, Cervical Assessment, Doppler Assessment, Istanbul, 16.11.2001 -18.11.2001
4. Prenatal Diagnosis and Treatment Course, Obstetric Ultrasonography, Prenatal Diagnosis and Treatment, I.U. Istanbul Faculty of Medicine, Department of Obstetrics and Gynecology, 27.04.1998 -01.05.1998
5. Andrology Course, Andrology, Antalya, Course, 25.09.1997 -25.09.1997 6. Course on Doppler-Ultrasonography in Gynecology, Antalya, 27.09.1997 -27.09.1997

1.Clinical Research and Good Clinical Practices Training for Ethics Committee Members and Candidates (2016)
2. Urgent Obstetrics Care Clinician Training (2015)
3. Laparoscopic Surgery Course, Laparoscopic Surgery, Endometriosis Adenomyosis Association (2012)
4. Assisted Reproduction Treatment Methods Certificate (2005)
5. Laparoscopy (2006)
6. Hysteroscopy (2005)
7. Neonatal Resuscitation Training (2002)


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